The HairMax LaserComb® and Laser Photo Therapy: Mechanism of Action Hypothesis
Although hundreds of clinical papers have been written about the positive attributes of low level laser therapy, the exact mechanism of action of the HairMax is still under clinical investigation. Users and clinical trial subjects have observed hair growth and hair cycle changes that are related to HairMax’s Laser PhotoTherapy properties. Therefore, the following hypotheses have been formed that attempt to explain the method of action of the HairMax.
The laser light of the HairMax penetrates the scalp and hair follicles in a consistent manner via its patented hair parting teeth system. The teeth of the HairMax part the hair to allow for precision delivery of laser light to all areas of the scalp and an unobstructed path to the hair follicle. Without the patented hair parting teeth, as much as 90% of the laser light energy can be blocked by the hair. Remember, the treatment is most effective when the laser path is unobstructed.
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With hair parting teeth
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Without hair parting teeth
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View of the Hair Parting Mechanism in Action. This is a simulated view from the scalp facing towards the path of the LaserComb. As you can see, without hair parting teeth, the majority of the laser energy is blocked by the hair itself.
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Anagen Induction and Accelerated Hair Growth
It is hypothesized that Laser PhotoTherapy applied to the scalp directly affects the hair follicle by Photo-Bio Stimulation leading to Anagen Induction. This process, in which the laser light bathes the scalp and follicular cells, causes an increase in ATP and Keratin Production and the stimulation of hair growth. Users routinely report faster hair growth during treatment with the HairMax which may be attributable to the above mentioned hypothesis.

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Embryology of Hair Development
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Cell Proliferation of the Epithelia Associated with Terminalization of Hair
It is further hypothesized that the laser light of the HairMax causes cell proliferation in the epithelia of the hair follicle marked by thicker hair growth and an increase in shedding of Catagen hairs at the onset of treatment. Since the dermal papilla consists of certain fibroblasts and specialized matrix cells at the base of the hair follicle, the laser light of the HairMax apparently interacts with these cells causing cell proliferation. In support of this assumption are consistent user reports of shedding at the onset of treatment and clinical trial results demonstrating distinct terminalization of hairs formerly in the vellus phase.
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Clinically Proven to Promote Hair Growth* |
Greater than 90% User Satisfaction Reported |
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* The HairMax LaserComb is cleared for marketing by the FDA for The Promotion of Hair Growth in males with Androgenetic Alopecia who have Norwood Hamilton Classifications of IIa-V and Fitzpatrick Skin Types I to IV